| 胚胎早裂联合胚胎发育速度及形态评分在胚胎选择中的应用 |
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| 引用本文： | 孙贻娟,张爱军,陆小溦,牛志宏,陈骞,冯云. 胚胎早裂联合胚胎发育速度及形态评分在胚胎选择中的应用[J]. 上海交通大学学报(医学版), 2009, 29(6) |
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| 作者姓名： | 孙贻娟 张爱军 陆小溦 牛志宏 陈骞 冯云 |
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| 作者单位： | 上海交通大学医学院瑞金医院生殖医学中心,上海200025 |
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| 摘 要： | 目的探讨胚胎早裂联合胚胎发育速度及形态评分对于体外授精／卵母细胞单精子显微注射（IVF／ICSI）周期中胚胎选择的意义。方法IVF／ICSI610周期，随机分为A、B两组。A组（269周期）单以授精后72h（D3）胚胎发育速度及形态评分选择胚胎；B组（341周期）在此基础上联合胚胎早裂情况进行胚胎选择。比较两组的临床妊娠率和单胚着床率；比较B组移植胚胎中有早裂胚胎和无早裂胚胎者的妊娠结局。结果B组临床妊娠率和单胚着床率均高于A组（P〈0．05）；B组移植胚胎中有早裂胚胎者的临床妊娠率和单胚着床率均高于无早裂胚胎者（P〈0．01）。结论与单纯的胚胎发育速度及形态评分比较，胚胎早裂联合胚胎发育速度及形态评分进行胚胎评价可显著改善IVF／ICSI的临床结局。
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| 关 键 词： | 胚胎评价 早裂 体外受精-胚胎移植 卵母细胞单精子显微注射 |
Application of early cleavage embryo in combination with embryo growth rate and morphology scoring in embryo selection |
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| SUN Yi-juan,ZHANG Ai-jun,LU Xiao-wei,NIU Zhi-hong,CHEN Qian,FENG Yun. Application of early cleavage embryo in combination with embryo growth rate and morphology scoring in embryo selection[J]. Journal of Shanghai Jiaotong University:Medical Science, 2009, 29(6) |
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| Authors: | SUN Yi-juan ZHANG Ai-jun LU Xiao-wei NIU Zhi-hong CHEN Qian FENG Yun |
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| Affiliation: | Reproductive Medical Center;Ruijin Hospital;School of Medicine;Shanghai Jiaotong University;Shanghai 200025;China |
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| Abstract: | Objective To evaluate the role of early cleavage embryo in combination with embryo growth rate and morphology scoring in embryo selection in in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI) cycles.Methods Six hundred and ten IVF/ICSI cycles were randomly assigned to group A(269 cycles) and group B(341 cycles).In group A, transferred embryos were chosen according to embryo growth rate and morphology scoring by 72 h(D3) after fertilization, while early cleavage embryo was added to the selecti... |
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| Keywords: | embryo evaluation early cleavage in vitro fertilization and embryo transfer intracytoplasmic sperm injection |
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