| 脑缺血后的神经发生与凋亡 |
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| 引用本文： | 吴晓黎,何志义. 脑缺血后的神经发生与凋亡[J]. 国际脑血管病杂志, 2004, 12(10): 778-781 |
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| 作者姓名： | 吴晓黎 何志义 |
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| 作者单位： | 110001,沈阳,中国医科大学第一临床学院神经内科;110001,沈阳,中国医科大学第一临床学院神经内科 |
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| 摘 要： | 研究表明 ,成年哺乳动物脑内存在神经干细胞 ,具有神经发生的能力。在脑缺血后 ,神经干细胞被激活 ,分化为神经元并可替代丢失的神经细胞 ,发挥一定的代偿功能 ,同时其他一些细胞却发生凋亡。文章介绍了脑缺血后神经发生和凋亡的研究新进展 ,而促进神经发生 ,减少凋亡会是一条新的治疗新思路
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| 关 键 词： | 神经发生 凋亡 脑缺血 |
| 修稿时间： | 2004-07-20 |
Neurogenesis and Apoptosis After Cerebral Ischemia |
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| Wu Xiaoli,He Zhiyi. Neurogenesis and Apoptosis After Cerebral Ischemia[J]. International Journal of Cerebrovascular Diseases, 2004, 12(10): 778-781 |
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| Authors: | Wu Xiaoli He Zhiyi |
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| Affiliation: | Wu Xiaoli,He Zhiyi Department of Neurology,the First Clinical College of China Medical University,Shenyang 110001,China |
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| Abstract: | Studies ha ve demonstrated that there are neural stem cells(NSCs)in the adult mammalian b rain, and they have the capability of neurogenesis. NSCs are activated and diffe rentiated into neurons after cerebral ischemia, and replace the lost nerve cells , performing their certain compensatory functions. Meanwhile some other cells co mmit suicide(apoptosis). This article briefly elucidates the recent developmen t in neurogenesis and apoptosis after cerebral ischemia, but it may be a novel t herapeutic thinking in promoting neurogenesis and reducing apoptosis. |
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| Keywords: | neurogenesis apoptosis cerebral ischemia |
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