Preparation of vaccines against H5N1 influenza |
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Authors: | Wood J M Major D Newman R W Dunleavy U Nicolson C Robertson J S Schild G C |
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Affiliation: | National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, UK. jwood@nibsc.ac.uk |
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Abstract: | In response to the pandemic warning provided by the highly pathogenic H5N1 influenza virus infections in Hong Kong, there were world-wide attempts to develop vaccines. Three strategies were followed and although each was associated with some success, there were also some problems. Pre-clinical vaccine efficacy results are presented from one such strategy, that of using an apathogenic H5N3 avian strain for vaccine production. |
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