| 自身免疫性疾病中抗核抗体与抗ENA抗体的相关性分析 |
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| 引用本文： | 赖永才,毛炜. 自身免疫性疾病中抗核抗体与抗ENA抗体的相关性分析[J]. 检验医学与临床, 2011, 8(7): 815-816. DOI: 10.3969/j.issn.1672-9455.2011.07.021 |
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| 作者姓名： | 赖永才 毛炜 |
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| 作者单位： | 四川省简阳市人民医院检验科,641400 |
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| 摘 要： | 目的探讨抗核抗体(ANA)荧光核型与抗可提取性核抗原抗体(ENA)之间的相关性。方法 ANA采用间接免疫荧光法检测,抗ENA抗体采用德国欧蒙公司免疫斑点法检测,检测结果采用双盲对照法分析。结果 132例抗ENA抗体阳性病例ANA的阳性率为93.9%,荧光核型主要以颗粒型为主。另外检测的103例ANA阳性病例中,抗ENA抗体常规6项阳性率为78.6%。结论抗ENA抗体类型与ANA荧光核型之间没有绝对的规律,临床检测自身抗体时需将两者结合分析。
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| 关 键 词： | 抗核抗体 抗可提取性核抗原抗体 荧光核型 |
Correlation analysis between ANA and anti-ENA antibody in autoimmune diseases |
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| LAI Yong-cai,MAO Wei. Correlation analysis between ANA and anti-ENA antibody in autoimmune diseases[J]. Laboratory Medicine and Clinic, 2011, 8(7): 815-816. DOI: 10.3969/j.issn.1672-9455.2011.07.021 |
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| Authors: | LAI Yong-cai MAO Wei |
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| Affiliation: | (Department of Laboratory,Jianyang Municipal People′ s Hospital,Jianyang,Sichuan 641400,China) |
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| Abstract: | Objective To study the correlation between fluorescent karyotype of antinuclear antibody(ANA) and antiextractable nuclear antigen(anti-ENA) antibody.Methods ANA was detected by indirect immunofluorescence assay and anti-ENA antibody was detected by Euro assay.The results were analyzed by double-blind control method.Results Among all 132 anti-ENA antibody positive cases,the positive rate for ANA was 93.9%,the fluorescent karyotype was mainly granular pattern.Among the 103 positive cases of ANA,the routine 6-... |
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| Keywords: | antinuclear antibody antiextractable nuclear antigen antibody fluorescent karyotype |
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