| 手足口病患儿治疗前后超敏C反应蛋白和肌酸激酶同工酶的变化及临床意义 |
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| 引用本文： | 雷鸿斌,王娴默,易光明. 手足口病患儿治疗前后超敏C反应蛋白和肌酸激酶同工酶的变化及临床意义[J]. 检验医学与临床, 2011, 8(1): 34-34,38. DOI: 10.3969/j.issn.1672-9455.2011.01.016 |
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| 作者姓名： | 雷鸿斌 王娴默 易光明 |
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| 作者单位： | 湖北省荆州市第一人民医院/长江大学附属第一医院,434000 |
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| 摘 要： | 目的观察手足口病患儿治疗前后超敏C反应蛋白(hs-CRP)的变化并探讨其临床意义。方法分别检测30例健康儿童、89例手足口病患儿治疗前和治疗7d后hs-CRP和肌酸激酶同工酶(CK-MB)水平。结果手足口病患儿组与健康对照组比较,治疗前hs-CRP和CK-MB升高差异有统计学意义(P<0.01)。经综合治疗7d后hs-CRP下降明显,与治疗前比较差异有统计学意义(P<0.01),而CK-MB变化无统计学意义。结论 hs-CRP是手足口病敏感而非特异的早期诊断指标,治疗前后检测对比可指导临床疗效判断。
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| 关 键 词： | 手足口病 C反应蛋白质 肌酸激酶 同工酶类 儿童 |
Clinical significance and changes of hs-CRP,CK-MB in HFMD children before and after treatment |
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| LEI Hong-bin,WANG Xian-mo,YI Guang-ming. Clinical significance and changes of hs-CRP,CK-MB in HFMD children before and after treatment[J]. Laboratory Medicine and Clinic, 2011, 8(1): 34-34,38. DOI: 10.3969/j.issn.1672-9455.2011.01.016 |
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| Authors: | LEI Hong-bin WANG Xian-mo YI Guang-ming |
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| Affiliation: | ( Jingzhou First People＇s Hospital, Jingzhou, Hubei 434000, China) |
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| Abstract: | Objective To observe the clinical significance and changes of hs-CRP,CK-MB in children infected with hand,foot and mouse disease（HFMD） before and after treatment. Methods 30 cases of healthy children and 89 cases of HFMD children were detected separately CK-MB and hs-CRP level before and after 7 d treatment. Results Before treatment,compared with the healthy control group,the level of hs CRP and CK-MB in HFMD children were significantly increased（P〈0.01）. After 7 d combined treatment,hs CRP content change of HFMD children was significantly lower than before（P〈0.01 ）, hut CK-MB content change of HFMD children had no statistical significance. Conclusion hs-CRP is an early, sensitive but non-specific indicator of diagnosing HFMD, which can guide clinical therapy judgment before and after treatment. |
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| Keywords: | hand,foot and mouth disease C reactive protein creatine kinase isoenzymes child |
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