| 乙型肝炎患者抗核抗体检测的临床价值 |
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| 引用本文： | 颜京瑞. 乙型肝炎患者抗核抗体检测的临床价值[J]. 检验医学与临床, 2011, 8(5): 572-573. DOI: 10.3969/j.issn.1672-9455.2011.05.027 |
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| 作者姓名： | 颜京瑞 |
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| 作者单位： | 南京东南大学附属南京江北人民医院,210048 |
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| 摘 要： | 目的 探讨检测乙型肝炎(简称乙肝),乙肝后肝硬化、肝癌患者血清中抗核抗体(ANA)的意义.方法 采用酶联免疫吸附试验(ELISA)对 395份血液标本进行ANA检测,其中乙肝组293例、乙肝后肝硬化组49例、肝癌组53例,健康对照组62例.结果 健康对照组ANA阳性3 例(4.8%)、乙肝组ANA均值为0.81,阳性54例(18.4%);肝硬化组ANA均值为1.09,阳性 19例(38.8%);肝癌组ANA均值为1.07,阳性21 例(39.6%).各组与健康对照组比较差异均有统计学意义(P<0.05);肝硬化组、肝癌组与乙肝组比较差异有统计学意义(P<0.05);乙肝后肝硬化与肝癌差异无统计学意义(P>0.05).结论 ANA的检测对乙肝的预后判断、发展和转归有一定意义.
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| 关 键 词： | 肝炎,乙型 抗核抗体 酶联免疫吸附试验 肝硬化 肝肿瘤 |
Clinical value of anti-nuclear antibody test in patients with hepatitis B |
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| YAN Jing-rui. Clinical value of anti-nuclear antibody test in patients with hepatitis B[J]. Laboratory Medicine and Clinic, 2011, 8(5): 572-573. DOI: 10.3969/j.issn.1672-9455.2011.05.027 |
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| Authors: | YAN Jing-rui |
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| Affiliation: | YAN Jing-rui(Affiliated Jiangbei Hospital,Southeast University,Nanjing,Jiangsu 210048,China) |
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| Abstract: | Objective To investigate the significance of the anti-nuclear antibody(ANA)test in serum for the patients with hepatitis B(HB),HB-liver cirrhosis and liver cancer.Methods Enzyme-linked immunosorbent assay(ELISA)was used for ANA test on 395 blood specimens,including 293 cases of HB,49 cases of HB-liver cirrhosis,53 cases of liver cancer and 62 healthy controls.Results In control group,3 cases(4.8%)were ANA positive;in HB group,ANA mean was 0.81 and positive in 54 cases(18.4%);in HB-liver cirrhosis group,ANA ... |
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| Keywords: | hepatitis B anti-nuclear antibody enzyme-linked immunosorbent assay liver cirrhosis liver cancer |
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