424例痰培养病原菌菌谱和耐药性分析

目的监测痰标本的病原菌菌谱及其耐药性,为临床经验用药和医院感染控制提供依据。方法对424例痰培养阳性标本的鉴定结果和药敏试验结果进行回顾性分析。结果 424例痰培养病原菌主要为革兰阴性杆菌(81.8%),病原菌前5位依次为肺炎克雷伯菌、副流感嗜血杆菌、铜绿假单胞菌、大肠埃希菌和金黄色葡萄球菌。革兰阴性杆菌对氨苄西林耐药率达92.3%,铜绿假单胞菌、鲍曼复合醋酸钙不动杆菌对1、2代头孢菌素,头孢西丁,呋喃妥因等抗菌药物的耐药率在80%～100%,葡萄球菌属对青霉素G耐药率为93.4%。结论痰标本病原菌仍以革兰阴性杆菌为主,且对常用抗菌药物的耐药性均较高。

Analysis of pathogen spectrum and drug resistance in 424 cases of sputum culture

Objective To investigate the pathogen spectrum and drug resistance of sputum specimens and provide some evidence for clinical experience medication and infection control.Methods The pathogenic bacteria and the drug resistance of 424 cases of positive sputum culture were analyzed retrospectively.Results The major pathogenic bacteria were Gram negative bacteria(81.8%),and the detection rates were in turn Klebsiella pneumoniae,Pseudomonas aeruginosa,Haemophilus,Escherichia coli and Staphylococcus aureus.The dr...