超声引导下经皮射频毁损肝癌疗效分析及安全性评价

目的：探讨经皮射频(radio frequency,RF)治疗对肝癌的疗效，并对其适应证，禁忌证及不良反应进行评价。方法：154例原发性或继发性肝癌者，肿块平均直径为7．07cm。采用RF2000TM射频治疗仪，于B超引导下进行射频消，观察疗效及并发症。结果154例患者共行182次治疗，平均每例治疗1．18次，每次治疗5．74 。治疗后症状有改善，AFP平均浓度由治疗前的1553．68ng/ml下降到883．70ng/ml，肿块缩小率为56．85，无致死性或严重致残性的并发症发生。结论：经皮射频治疗肝癌方法简单，安全有效，大肝癌可分次治疗，但需与其他介入治疗等联合应用以提高疗效。

Percutaneous radio frequency ablation of liver cancer guided by ultrasonograhy

Objective To investigate the effects of percutaneous radio frequency ablation of liver cancer, and evaluate the indications, contraindications, and side effects. Methods One hundred and fifty four patients with hepatocellular carcinoma or metastases liver cancer, with the average diameter of the tumours 7.07 cm were treated with by radio frequency RF 2000TM instrument, the results were evaluated. Results Average theraputic time was 1.18 times, the theraputic point was 5.74. The symptoms were improved after therapy, and the average concentration of AFP was droped from 1 553.68 ng/ml to 883.70 ng/ml. The percentage of tumour reduction was 56.8%. There were no serious complications observed. Conclusion Percutaneous radio frequency ablation of liver cancer is a simple, safe and effective method. For larger liver cancer several times action will be needed, or other intervantion therapy is added to enhance effectiveness.