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胃癌腹腔灌洗液CEA测定的临床意义
引用本文:朱孝成 林超鸿. 胃癌腹腔灌洗液CEA测定的临床意义[J]. 中国肿瘤临床, 1997, 24(2): 89-91
作者姓名:朱孝成 林超鸿
作者单位:徐州医学院附属医院外科!江苏省徐州市,221002(朱孝成),上海市第六人民医院外科(林超鸿)
摘    要:检测50例胃癌和10例胃良性病变腹腔灌洗液CEA及脱落细胞,CEA临界值定为115ng/g蛋白。结果:胃癌腹膜种植、侵及装膜、未侵及浆膜,CEA阳性率分别为88.9%、55.8%、13.3%。三者差异显著(P<0.01)。CEA阳性组2年1存率(29.2%),显著低于阴性组(88.5%)(P<0.05)。提示腹腔灌洗液CEA检测比脱落细胞检查更准确、敏感,是判断腹膜隐性播散和预后的一种好方法。

关 键 词:胃癌  腹腔灌洗液  CEA  预后

Determination of CEA in Peritoneal Irrigation Fluid in Gastric Cancer Patients
Abstract:CEA levels and exfoliative cells in peritoneal irrigation fluid were determined in 50 gastric cancer patients and 10 with benign lesions.The results showed that the CEA positive rates in patients with visible peritoneal dissemina tion,serosal invasion and non-invaded peritoneum were 88.9%,55.8%,13.3% re spectively.2-year survival rate of CEA positive patients was markedly lower than that of the negative group.It is concluded that determination of CEA in peritoneal irrigation fluid is superior to the exfoliative cystologic examination in terms of accu racy and sensitivity,and it is and ideal means for prognosis evaluation.
Keywords:Gastric cancer Peritoneal irrigation fluid CEA Prognosis
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