| 康脑灵胶囊对痴呆大鼠学习记忆能力及对AchE、NGF表达的影响 |
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| 引用本文： | 季旭明,张鸿婷. 康脑灵胶囊对痴呆大鼠学习记忆能力及对AchE、NGF表达的影响[J]. 中医药信息, 2006, 23(3): 54-56 |
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| 作者姓名： | 季旭明 张鸿婷 |
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| 作者单位： | 1. 山东中医药大学,山东,济南,250014
2. 黑龙江中医药大学附属二院,黑龙江,哈尔滨,150040 |
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| 摘 要： | 目的:探讨康脑灵胶囊对痴呆大鼠学习记忆能力的影响;方法:复制大鼠VD模型,采用Y-型迷宫及跳台计数仪,定量测定学习记忆能力,分光光度法检测MAO、AchE含量,免疫组化法检测AchE、NGF表达;结果:康脑灵胶囊明显增强模型动物的学习记忆能力,降低MAO、AchE含量,提高AchE、NGF表达;结论:康脑灵胶囊明显改善VD大鼠的学习记忆能力。
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| 关 键 词： | 康脑灵胶囊 学习记忆能力 实验研究 |
| 文章编号： | 1002-2406(2006)02-0054-02 |
| 收稿时间： | 2006-01-07 |
| 修稿时间： | 2006-01-07 |
Effect of Kangnaoling Capsule on learning and memory ability and expression of ache and ngf of vd rats |
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| JI Xu-ming,ZHANG Hong-ting. Effect of Kangnaoling Capsule on learning and memory ability and expression of ache and ngf of vd rats[J]. Information on Traditional Chinese Medicine, 2006, 23(3): 54-56 |
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| Authors: | JI Xu-ming ZHANG Hong-ting |
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| Abstract: | Objective:To study the effects of Kangnaoling capsule on learning and memory ability of VD rats.Methods:Duplicating VD animal model,Quantitating the learning and memory ability by using Y-maze and jumping stand,detecting contents of MAO and AchE through spectrophotometry,detecting expressions of AchE and NGF through immunohistochemical method.Results:Kangnaoling capsule can markedly enhance the ability AchE;Conclusions:Kangnaoling capsule can significantly improve the ability of learning and memory of VD rats. |
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| Keywords: | AchE NGF |
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