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康脑灵胶囊对痴呆大鼠学习记忆能力及对AchE、NGF表达的影响
引用本文:季旭明,张鸿婷.康脑灵胶囊对痴呆大鼠学习记忆能力及对AchE、NGF表达的影响[J].中医药信息,2006,23(3):54-56.
作者姓名:季旭明  张鸿婷
作者单位:1. 山东中医药大学,山东,济南,250014
2. 黑龙江中医药大学附属二院,黑龙江,哈尔滨,150040
摘    要:目的:探讨康脑灵胶囊对痴呆大鼠学习记忆能力的影响;方法:复制大鼠VD模型,采用Y-型迷宫及跳台计数仪,定量测定学习记忆能力,分光光度法检测MAO、AchE含量,免疫组化法检测AchE、NGF表达;结果:康脑灵胶囊明显增强模型动物的学习记忆能力,降低MAO、AchE含量,提高AchE、NGF表达;结论:康脑灵胶囊明显改善VD大鼠的学习记忆能力。

关 键 词:康脑灵胶囊  学习记忆能力  实验研究
文章编号:1002-2406(2006)02-0054-02
收稿时间:2006-01-07
修稿时间:2006年1月7日

Effect of Kangnaoling Capsule on learning and memory ability and expression of ache and ngf of vd rats
JI Xu-ming,ZHANG Hong-ting.Effect of Kangnaoling Capsule on learning and memory ability and expression of ache and ngf of vd rats[J].Information on Traditional Chinese Medicine,2006,23(3):54-56.
Authors:JI Xu-ming  ZHANG Hong-ting
Abstract:Objective:To study the effects of Kangnaoling capsule on learning and memory ability of VD rats.Methods:Duplicating VD animal model,Quantitating the learning and memory ability by using Y-maze and jumping stand,detecting contents of MAO and AchE through spectrophotometry,detecting expressions of AchE and NGF through immunohistochemical method.Results:Kangnaoling capsule can markedly enhance the ability AchE;Conclusions:Kangnaoling capsule can significantly improve the ability of learning and memory of VD rats.
Keywords:AchE  NGF
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