New antiepileptic drugs: Prospects for the future |
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| Affiliation: | 1. Sensory-Motor Laboratory (SeMoLa), Jules-Gonin Eye Hospital/Fondation Asile des Aveugles, Department of Ophthalmology/University of Lausanne, Lausanne, Switzerland;2. InBrain Lab, Department of Physics, University of São Paulo, Ribeirão Preto, Brazil;3. Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zürich, Switzerland;4. Institute of Systems Neuroscience, Heinrich Heine University Düsseldorf, Düsseldorf, Germany;5. Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7), Research Centre Jülich, Jülich, Germany;6. Department of Radiology and Biomedical Imaging, Yale School of Medicine, Yale University, New Haven, CT, USA;7. Department of Neuroradiology, University Hospital Zurich, Zurich, Switzerland;8. Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology, Zurich, Switzerland;9. Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland;10. Department of Cognition, Emotion, and Methods in Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria |
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| Abstract: | Considerable advances have been made in the understanding of the pathophysiology of epilepsy, which has led to the development of a large number of unique antiepileptic drugs affecting a broader array of pharmacological targets than traditional anticonvulsants. In this paper we discuss seven anticonvulsants that are either recently released, or are being actively investigated in the United States. A review of their pharmacological properties and clinical efficacy is presented. |
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