家庭干预对分裂情感性精神障碍患者生活质量的影响研究

目的探讨家庭干预对分裂情感性精神障碍患者生活质量的影响。方法于2012年1月-2013年12月在苏州市广济医院精神科选取符合《中国精神障碍分类与诊断标准(第3版)》(CCMD-3)的135例分裂情感性精神障碍患者为研究对象,按照最小不平衡指数法分为对照组(n=67)和研究组(n=68),两组均采用盐酸氯丙嗪片治疗并进行常规处理,研究组同时进行每3个月1次的家庭干预,共8次。采用躁狂评定量表(YMRS)和汉密尔顿抑郁量表(HAMD)评定患者的不良情绪,采用生活质量综合评定问卷(GQOLI-74)评定患者的生活质量情况。结果干预后,两组YMRS评分和HAMD评分均较干预前下降(t=4.24~12.35,P均0.05),且研究组优于对照组(t=5.47,9.37,P均0.05);研究组躯体功能、心理功能、社会功能和总体生活质量评分均高于对照组(t=7.23~13.01,P均0.05)。结论家庭干预可改善分裂情感性精神障碍的症状,提高生活质量。

Study on the effect of family intervention on schizoaffective disorder

[Abstract]Objective To investigate the effect of family intervention on schizoaffective disorder. Methods 135 cases of patients with schizoaffective disorderaccording with the ＂ Chinese classification and diagnostic criteria of mental disorders （ Third Edition） ＂ （ CCMD - 3 ） were divided into study group and control group according to minimum unbalance index methods in psychiatric department of Suzhou Guangji Hospital, 67 cases of patients in the control group were treated with Chlorpromazine Hydrochloride Tablets, and also for routine care ; 68 cases of patients in study group were treated by antipsychotic medication and given the family intervention at the same time. Two groups of patients used the same medication and same dose. To evaluate the negative emotions ot patients by using the Mania Rating Scale （Young ManicRating Scale, YMRS ） and Hamilton Depression Scale （Hamilton Depression Scale, HAMD） , the quality of life of patients was assessed by using the general quality of life questionnaire （ Generic Quality of Life （ Inventory- 74, GQOLI -74 ）. Results All patients after treatment, YMRS score and HAMD scores were significantly higher than before treatment （ t = 4. 24 ~ 12. 35, all P 〈 0.05 ） , and after care, YMRS score and HAMD scores of research group were significantly better than the control group （ t = 5.47,9.37, all P 〈 0.05 ） ; Physical function, psychological function, social function and overall quality of life scores of patients in study group were significantly higher than these of control group （ t = 7.23 - 13.01, all P 〈 0.05 ） ; There was no obvious difference in living state between two groups （ t = 2.85, P 〉 0.05 ）. Conclusion Family intervention can significantly improve the schizoaffective disorder, promote their comprehensive rehabilitation, reduce bad mood events, improve life the quality.