| 实验性肝硬化门脉血流动力学变化与胰高糖素的关系 |
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| 引用本文： | 王先明,文明星,房献平,金庆达.实验性肝硬化门脉血流动力学变化与胰高糖素的关系[J].中南大学学报(医学版),1989(4). |
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| 作者姓名： | 王先明 文明星 房献平 金庆达 |
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| 作者单位： | 湖南医科大学第二附属医院外科
(王先明,文明星,房献平),湖南医科大学第二附属医院外科(金庆达) |
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| 摘 要： | 用肝硬化大鼠动物模型,观察了肝硬化大鼠不同时期门脉血流动力学与胰高糖素的关系。肝硬化大鼠的血清胰高糖素显著增高,早期尤为明显;同时,门脉血流量和门脉压力也明显上升。提示在门脉高压症发病机制中,胰高糖素对门脉高压症的形成起了重要作用。
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| 关 键 词： | 肝硬化 实验性 病因学 血流动力学 门脉高压症 胰高糖素 大鼠 |
PORTAL HEMODYNAMIC ALTERATION AND GLUCAGON IN EXPERIMENTAL LIVER CIRRHOSIS |
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| Wang Xianming Wen Mingxing Fang Xianping Jin Qingda.PORTAL HEMODYNAMIC ALTERATION AND GLUCAGON IN EXPERIMENTAL LIVER CIRRHOSIS[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1989(4). |
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| Authors: | Wang Xianming Wen Mingxing Fang Xianping Jin Qingda |
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| Institution: | Wang Xianming Wen Mingxing Fang Xianping Jin QingdaDepartment of Surgery,The Second Affiliated Hospiral,Hunan Medical University |
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| Abstract: | Serum glucagon level and portal hemodynamic alteration in development of experimental liver cirrhosis was investigated. Serum glucagon increased significantly when cirrhosis is developing at the initial stage, portal blood flow volume and pressure increased concommitantly. Glucagon might play an important role in the pathogenesis of portal hypertension. " |
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| Keywords: | liver cirrhosis experimental portal hypertension glucagon etiology rats |
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