|
|||||
|
|
Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status |
|
| Authors: | Imad Abboud Nicolas Lerolle Saik Urien Jean-Marc Tadié Françoise Leviel Jean-Yves Fagon Christophe Faisy |
| Institution: | 1. Medical Intensive Care Unit, H?pital Européen Georges Pompidou, Assistance Publique-H?pitaux de Paris, Université Paris– Descartes, Paris, France 2. E.A. 3620, CIC-0109 Cochin-Necker Paris Descartes, Unité de Recherche Clinique, Tarnier Hospital, Assistance Publique-H?pitaux de Paris, Université Paris – Descartes, Paris, France 3. Department of Physiology, H?pital Européen Georges Pompidou, Assistance Publique-H?pitaux de Paris, Université Paris – Descartes, Paris, France |
| Abstract: | IntroductionIn septic patients, an unpredictable response to epinephrine may be due to pharmacodynamic factors or to non-linear pharmacokinetics. The purpose of this study was to investigate the pharmacokinetics of epinephrine and its determinants in patients with septic shock. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |