Percutaneous image-guided radiofrequency ablation of liver tumors |
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Authors: | Riccardo Lencioni Laura Crocetti Maria Clotilde Della Pina Dania Cioni |
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Institution: | (1) Division of Diagnostic Imaging and Intervention, Department of Hepatology and Liver Transplantation, Pisa University Hospital, Via Paradisa 2, Pisa, 56124, Italy;(2) Division of Diagnostic Radiology, Department of Oncological and Radiological Sciences, Pisa University Hospital, Via Paradisa 2, Pisa, 56124, Italy |
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Abstract: | The development of image-guided percutaneous techniques for local tumor ablation has been one of the major advances in the
treatment of liver malignancies. Over the past two decades, several methods for chemical or thermal tumor destruction have
been clinically tested. Among these methods, radiofrequency (RF) ablation is currently established as the primary ablative
modality at most institutions. RF ablation is accepted as the best therapeutic choice for patients with early-stage hepatocellular
carcinoma (HCC) when liver transplantation or surgical resection are not suitable options. In addition, RF ablation is emerging
as a viable alternate to surgery for inoperable patients with limited hepatic metastatic disease, especially from colorectal
cancer. Several series have shown that RF ablation can result in complete tumor eradication in properly selected candidates,
and have provided indirect evidence that the treatment improves survival. In this article, we review technique, indications,
and clinical results of percutaneous RF ablation in the treatment of HCC and colorectal hepatic metastases. |
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