Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B |
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Authors: | Christopher D. Lowe M.D. Rebecca J. Sainato M.D. David R. Stagliano M.D. Maribel M. Morgan M.D. Brian P. Green D.O. |
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Affiliation: | 1. Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland;2. Department of Pediatric Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, Maryland;3. Department of Pediatrics, San Antonio Military Medical Center, San Antonio, Texas |
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Abstract: | Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions. This case highlights the importance of rapid and thorough evaluation of skin lesions when evaluating preterm infants and other immunocompromised patients, even when other sources of infection have been identified. |
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