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Trichodysplasia Spinulosa in a 7‐Year‐Old Boy Managed Using Physical Extraction of Keratin Spicules
Authors:Michael Barton MD  Suing Lockhart ARNP  Robert Sidbury MD  Richard Wang MD  Heather Brandling‐Bennett MD
Institution:1. Billings Clinic Internal Medicine Residency, Billings, Montana;2. Pediatric Dermatology, University of Washington, Seattle, Washington;3. University of Texas Southwestern Medical Center, Dallas, Texas
Abstract:Trichodysplasia spinulosa (TS) is an uncommon skin disease characterized by a folliculocentric papular eruption and keratin spine formation, classically appearing on the central face and ears. It occurs in immunosuppressed patients and is linked to a viral etiology. Diagnostic tests including polymerase chain reaction (PCR) are available for detection of the TS‐associated polyomavirus. Effective treatment options include topical cidofovir and oral valganciclovir. We present a case diagnosed using PCR with skin scrapings and treated using physical extraction of the keratin spicules. Significant improvement was noted, suggesting a safe, cost‐effective treatment alternative.
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