| 劳拉西泮与碳酸锂治疗躁狂症的比较 |
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| 引用本文： | 王年生,李志成,宫玉祥,初建峰.劳拉西泮与碳酸锂治疗躁狂症的比较[J].中国新药与临床杂志,1996(2). |
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| 作者姓名： | 王年生 李志成 宫玉祥 初建峰 |
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| 作者单位： | 济宁市精神病防治院 |
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| 摘 要： | 目的：评估劳拉西泮对躁狂症的疗效。方法：用劳拉西泮治疗男性躁狂症１９例（年龄２８±ｓ１０ａ，病程２．０±１．３ｍｏ），剂量６～１８ｍｇ／ｄ，疗程３ｗｋ，并与碳酸锂治疗男性躁狂症２０例（年龄２８±１１ａ，病程２．０±１．３ｍｏ）对照，剂量１．５～２．５ｇ／ｄ，疗程３ｗｋ。结果：劳拉西泮组，总有效率８９％，碳酸锂组，总有效率９５％（Ｐ＞０．０５），但劳拉西泮起效时间较碳酸锂为早，不良反应以嗜唾、头晕为主。结论：劳拉西泮可作为控制躁狂症急性发作的有效药物。
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| 关 键 词： | 劳拉西泮 锂 躁狂性精神病 |
Lorazepam vs lithium carbonate in treatment of mania |
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| WANG Nian-Sheng, LI Zhi-Cheng, GONG Yu-Xiang, CHU Jian-Feng.Lorazepam vs lithium carbonate in treatment of mania[J].Chinese Journal of New Drugs and Clinical Remedies,1996(2). |
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| Authors: | WANG Nian-Sheng LI Zhi-Cheng GONG Yu-Xiang CHU Jian-Feng |
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| Abstract: | AIM: To evaluate the therapeutic effect of lorazepam for mania. METHODS: Nineteen male patients with mania (age 28 ±s 10 a, course 2.0±1.3mo) were treated with lorazepam 6-18 mg/d for 3 wk. Other similar 20 male patients (age 28±11 a, course 2.0±1.3 mo) received lithium carbonate 1.5-2.5g/d for 3 wk. RESULTS: The total response rate of lorazepam group was 89%, that of lithium carbenate group was 95% (P>0.05), but the onset of effect was earlier in the lorazepam group. The main adverse reactions were drowsiness and dizziness. CONCLUSION: Lorazepam can be used to control acute stage of mania. |
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| Keywords: | lorazepam lithium manic disorder |
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