| 注射用紫杉醇纳米制剂的研究进展 |
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| 引用本文： | 雷景邦,刘旭海,万瑾瑾,叶民珠,邹富有.注射用紫杉醇纳米制剂的研究进展[J].中国新药与临床杂志,2010(6). |
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| 作者姓名： | 雷景邦 刘旭海 万瑾瑾 叶民珠 邹富有 |
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| 作者单位： | 江西中医学院;江西江中药业股份有限公司; |
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| 摘 要： | 紫杉醇广泛用于卵巢癌、乳腺癌、肺癌等多种肿瘤的治疗。传统的紫杉醇制剂生物利用度低,临床应用有限。纳米给药系统是现代药物制剂的研究热点,近年来临床上陆续开发了紫杉醇的纳米新剂型。纳米乳、纳米粒、胶束等也正在实验研究之中。本文就紫杉醇纳米制剂的开发和应用进展进行综述。
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| 关 键 词： | 紫杉醇 抗肿瘤药 纳米制剂 |
Advances of nanoparticle formulation for injectable paclitaxel |
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| LEI Jing-bang,LIU Xu-hai,WAN Jin-jin,YE Min-zhu,ZOU Fu-you.Advances of nanoparticle formulation for injectable paclitaxel[J].Chinese Journal of New Drugs and Clinical Remedies,2010(6). |
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| Authors: | LEI Jing-bang LIU Xu-hai WAN Jin-jin YE Min-zhu ZOU Fu-you |
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| Institution: | LEI Jing-bang1,LIU Xu-hai2,WAN Jin-jin1,YE Min-zhu1,ZOU Fu-you1(1.Jiangxi University of Traditional Chinese Medicine,Nanchang JIANGXI 330004,China,2.Jiangxi Jiangzhong Pharmaceutical Co.,Ltd.,Nanchang JIANGXI 330096,China) |
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| Abstract: | Paclitaxel is widely used in ovarian cancer,breast cancer,lung cancer and other tumor treatment.Clinical application of this highly effective drug in the treatment of cancer is limited because of its poor bioavailability.Nanoparticle drug delivery system research is the focus of modern pharmaceutical formulation.A variety of nanoparticle formulations such as nano-emulsion,nanoparticles,micellars,etc.are also in research.This paper reviews the latest development and application of novel paclitaxel nanopartic... |
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| Keywords: | paclitaxel antineoplastic agents nanoparticle |
| 本文献已被 CNKI 等数据库收录！ |
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