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| 精制芎归缓释滴丸的制备 | |
| 引用本文： | 李慧,边宝林,孟繁蕴,王一涛. 精制芎归缓释滴丸的制备[J]. 中国中药杂志, 2005, 30(10): 747-749 |
| 作者姓名： | 李慧 边宝林 孟繁蕴 王一涛 |
| 作者单位： | 1. 中国中医研究院,中药研究所,北京,100700;北京师范大学,中药资源与资源药物研究所,北京,100088 2. 中国中医研究院,中药研究所,北京,100700 3. 北京师范大学,中药资源与资源药物研究所,北京,100088 |
| 摘 要： | 目的:筛选水溶性和水不溶性载体的种类、配比,研究缓释滴丸剂的成型处方。方法:以圆整度、硬度、料液的黏度、流动性、易滴制程度、累计释放百分数等为考察指标,采用正交设计试验对精制芎归缓释滴丸的成型处方进行优选。结果与结论:按照选定的处方既能有一定的速释量,还能保证10h持续释药80%以上,达到了释药设计目的。 |
| 关 键 词： | 精制芎归滴丸 成型处方 缓释设计 |
| 文章编号： | 1001-5302(2005)10-0747-03 |
| 收稿时间： | 2004-12-06 |
Study on preparation of refined Xiong-gui sustained release pills |
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| LI Hui;BIAN Bao-lin;MENG Fan-yun;WANG Yi-tao. Study on preparation of refined Xiong-gui sustained release pills[J]. China Journal of Chinese Materia Medica, 2005, 30(10): 747-749 | |
| Authors: | LI Hui BIAN Bao-lin MENG Fan-yun WANG Yi-tao |
| Affiliation: | Institute of Chinese Material Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China. lihuiyiren@sina.com |
| Abstract: | Objective: To optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied. Method: An orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop. Result and Conclusion: According to the final optimal formula, the amount of drug release can be detected instantly, while remaining over 80% at 10 h. |
| Keywords: | refined Xiong-gui sustained release pills molding formula design of sustained release |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |