| 旋转调强与固定野调强治疗肝癌的剂量学比较 |
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| 引用本文： | 马长升,尹勇,刘同海,陈进琥,孙涛,林秀桐.旋转调强与固定野调强治疗肝癌的剂量学比较[J].中华放射医学与防护杂志,2010,30(5):581-584,590. |
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| 作者姓名： | 马长升 尹勇 刘同海 陈进琥 孙涛 林秀桐 |
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| 作者单位： | 山东省肿瘤医院放疗科物理室,山东省放射肿瘤学重点实验室,济南,250117 |
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| 摘 要： | 目的 比较旋转调强(RapidArc)与固定野调强放疗(IMRT)在肝癌治疗计划中的剂量学差异。方法 选择10例肝癌患者的CT数据,分别设计IMRT计划与单弧(RA1)和双弧(RA2)计划,比较设计计划的靶区剂量分布、危及器官受量、正常组织受量、机器跳数以及治疗时间。结果 RA1和RA2计划靶区剂量的最大值都低于IMRT(Z=-2.090、-2.666,P＜0.05),计划90%的处方剂量的适形指数低于IMRT(Z=-2.805、-2.809,P＜0.05);危及器官胃与小肠的V40也比IMRT计划低。但IMRT左肾平均剂量低于RapidArc计划组(Z=-1.988、-2.191,P＜0.05);正常组织的V5、V10和V15IMRT计划低于RapidArc计划组,V20、V25和V30IMRT计划高于RapidArc计划组。RapidArc计划机器跳数是IMRT计划的40%和46%,治疗时间是IMRT计划30%和40%。结论 两种技术设计的计划剂量分布均能满足临床要求,并且剂量分布基本一致。RapidArc计划的适形指数优于IMRT,危及器官剂量也比IMRT计划略有降低,正常组织的低剂量区RapidArc计划组与IMRT相比有先高后低的趋势,并且机器跳数少,治疗时间短。
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| 关 键 词： | 旋转调强 逆向调强放疗 肝癌 剂量学 |
| 收稿时间： | 1/6/2010 12:00:00 AM |
Dosimetric comparision between RapidArc and fixed gantry intensity modulated radiation therapy in treatment of liver carcinoma |
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| MA Chang-sheng,YIN Yong,LIU Tong-hai,CHEN Jin-hu,SUN Tao and LIN Xiu-tong.Dosimetric comparision between RapidArc and fixed gantry intensity modulated radiation therapy in treatment of liver carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2010,30(5):581-584,590. |
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| Authors: | MA Chang-sheng YIN Yong LIU Tong-hai CHEN Jin-hu SUN Tao and LIN Xiu-tong |
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| Institution: | Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China;Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China;Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China;Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China;Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China;Department of Radiation Physics, Shandong Tumor Hospital, Shandong Provincial Key Laboratory of Radio-oncology, Jinan 250117,China |
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| Abstract: | |
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| Keywords: | RapidArc IMRT Liver carcinoma Dosimetry |
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