| 抑郁症中医辨证分型与外周血神经递质的关系 |
| |
| 引用本文： | 杨慧敏,李跃华,杨京,赵海京,肖爽. 抑郁症中医辨证分型与外周血神经递质的关系[J]. 中国中医药信息杂志, 2011, 18(4): 14-16. DOI: 10.3969/j.issn.1005-5304.2011.04.007 |
| |
| 作者姓名： | 杨慧敏 李跃华 杨京 赵海京 肖爽 |
| |
| 作者单位： | 中国中医科学院西苑医院,北京,100091 |
| |
| 摘 要： | 目的研究抑郁症患者中医辨证分型与外周血神经递质的关系。方法采用病例对照研究的方法，共观察139例中医辨证为肝郁气滞、肝郁脾虚、肝郁痰阻、心脾两虚、心’肾不交型的抑郁症患者，分别与30例正常人对比，观察各组外周血5-羟色胺（5-HT）、去甲肾上腺素（NE）、多巴胺（DA）的差异。结果肝郁气滞组NE，肝郁脾虚、肝郁痰阻、心脾两虚及心肾不交组5-HT、NE、DA低于正常对照组，差异有统计学意义（P〈0．05，P〈0．01）；各组有一定比例5-HT及NE功能低下及亢进者与正常对照组比较差异有统计学意义（P〈0．05，P〈0．01）；肝郁气滞、心脾两虚组分别有29．03％、25％DA功能亢进者与正常对照组比较差异有统计学意义（P〈0．01）。结论大部分抑郁症患者外周血5-HT、NE、DA低于正常人，但有部分患者表现为5-HT、NE、DA功能亢进，且各证型5-HT、NE、DA功能水平不同。
|
| 关 键 词： | 抑郁症 中医辨证分型 神经递质 5-羟色胺 去甲肾上腺素 多巴胺 |
Relationship between TCM Syndrome Types and Peripheral Neurotransmitter of Major Depression Patients |
| |
| YANG Hui-min,LI Yue-hua,YANG Jing,ZHAO Hai-jing,XIAO Shuang. Relationship between TCM Syndrome Types and Peripheral Neurotransmitter of Major Depression Patients[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2011, 18(4): 14-16. DOI: 10.3969/j.issn.1005-5304.2011.04.007 |
| |
| Authors: | YANG Hui-min LI Yue-hua YANG Jing ZHAO Hai-jing XIAO Shuang |
| |
| Affiliation: | YANG Hui-min,LI Yue-hua,YANG Jing,ZHAO Hai-jing,XIAO Shuang(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China) |
| |
| Abstract: | Objective To study the relationship between TCM syndrome types and peripheral neurotransmitter of major depression(MD) patients.Methods One hundred and thirty-nine MD patients,with TCM syndrome types of liver qi stagnation,liver depression and spleen deficiency,liver depression and phlegm obstruction,deficiency of both heart and spleen,non-interaction of heart and kidney,were researched by case-control study.The indicators between each TCM syndrome type and 30 normal subjects of 5-HT,NE and DA in peripheral... |
| |
| Keywords: | major depression TCM syndrome types neurotransmitter 5-HT NE DA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
