| 紫参胶囊喷雾干燥制粒工艺研究 |
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| 引用本文： | 刘晓闯,陈浩,程志清. 紫参胶囊喷雾干燥制粒工艺研究[J]. 中国中医药信息杂志, 2011, 18(5): 53-54. DOI: 10.3969/j.issn.1005-5304.2011.05.021 |
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| 作者姓名： | 刘晓闯 陈浩 程志清 |
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| 作者单位： | 安徽中医学院第一附属医院,国家中医药管理局中药制剂三级实验室,安徽,合肥,230031 |
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| 摘 要： | 目的优选紫参胶囊喷雾干燥制粒最佳工艺条件。方法采用正交试验法，以大黄素含量及制得颗粒质量为评价指标。结果优选的最佳工艺条件是：喷雾速度15kg／h，雾化压力0．2MPa，进风温度110℃，物料温度65℃。结论正交试验优选出的最佳喷雾干燥制粒工艺合理、可靠，可用于紫参胶囊制备。
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| 关 键 词： | 紫参胶囊 喷雾干燥制粒 工艺研究 |
Technology Study of Spraying and Dry Granulation of Zishen Capsules |
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| LIU Xiao-chuang,CHEN Hao,CHENG Zhi-qing. Technology Study of Spraying and Dry Granulation of Zishen Capsules[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2011, 18(5): 53-54. DOI: 10.3969/j.issn.1005-5304.2011.05.021 |
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| Authors: | LIU Xiao-chuang CHEN Hao CHENG Zhi-qing |
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| Affiliation: | LIU Xiao-chuang,CHEN Hao,CHENG Zhi-qing(The First Affiliated Hospital of Anhui College of TCM,Grade 3 Laboratory of TCM Preparation,State Administration of TCM,Hefei 230031,China) |
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| Abstract: | Objective To select the optimum conditions for spraying and dry granulation of Zishen capsules. Methods The process was studied by orthogonal experimental design, with emodin content and granular mass as evaluation indexes. Results The optimum technological condition was determined： to spray at the speed of 15 kg/h and at atomization pressure of 0.2 MPa, the air temperature was 110 ℃and materiel temperature was 65 ℃. Conclution The optimum technological condition is reasonable and reliable, and can be used for Zishen capsules preparation. |
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| Keywords: | Zishen Capsules spraying and dry granulation technology study |
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