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反应停治疗难治性多发性骨髓瘤11例临床报告
引用本文:吴德沛,孙爱宁,唐晓文,傅铮铮,苗瞄,李建勇,夏学鸣,林宝爵. 反应停治疗难治性多发性骨髓瘤11例临床报告[J]. 苏州大学学报(自然科学版), 2000, 20(11): 997-998
作者姓名:吴德沛  孙爱宁  唐晓文  傅铮铮  苗瞄  李建勇  夏学鸣  林宝爵
作者单位:苏州大学附属第一医院血液科,江苏省血液研究所,苏州,215006  
摘    要:目的 为观察反应停治疗难治性浆细胞肿瘤的有效性和毒性。方法 共 11例难治性浆细胞肿瘤入选。每晚服用反应停 2 0 0~ 40 0mg。结果  1例因服药未满一月而删除 ,10例中部分缓解 3例 ,进步 3例 ,无效 4例。副作用可以耐受 ,便秘 (7/10 )最常见。结论  30 0~ 40 0mg/日反应停治疗难治性多发性骨髓瘤安全有效

关 键 词:反应停  治疗  多发性骨髓瘤

Clinical Report on Thalidomide for Treatment of 11 Cases Refractory Multiple Myeloma
Wu Depei Sun Aining Tang Xiaowei et al. Clinical Report on Thalidomide for Treatment of 11 Cases Refractory Multiple Myeloma[J]. Suzhou University Journal of Medical Science, 2000, 20(11): 997-998
Authors:Wu Depei Sun Aining Tang Xiaowei et al
Abstract:Objective To investigate the efficacy and toxicity on thalidomide in the treatment of refractory plasma cell neoplasms. Method Oral thalidomide was given to 11 patients at doses of 200-400mg every evening. Results Among the 10 evaluative patients three achieved partial remission (PR) ,3 improved and 4 had no effect. Side effects could been tolerate and the most common one was constipation (7/10). Conclusion Thalidomide at doses of 300-400mg/d for the treatment of refractory plasma cell neoplasms is safe and effective .
Keywords:thalidomide  treatment  multiple myeloma
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