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ADRENAL GLUCOCORTICOID FUNCTION IN ACUTE VIRAL INFECTIONS IN CHILDREN
Authors:M. M. ZEITOUN  A. I. HASSAN  Z. M. HUSSEIN  M. S. FAHMY  M. RAGAB  M. HUSSEIN
Affiliation:Department of Paediatrics, Allexandria University, the Institute of Medical Research, and the Department of Statistics, High Institute of Public Health, Alexandria, Egypt
Abstract:The hypothalamic pituitary adrenal system was studied in normal Egyptian children and in groups of children with some common viral infections including measles, chicken pox, mumps and poliomyelitis. Results showed a significant rise in plasma 17-OHCS levels in all acute viral infections. ACTH and metyrapone tests revealed that the hypothalamic-pituitary-adrenal axis was functioning adequately. The value of corticosteroids in the management of acute viral infections is discussed in the light of our clinical and laboratory findings.
Keywords:Adrenalglucocorticoidfunction    acute viral infections
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