ADRENAL GLUCOCORTICOID FUNCTION IN ACUTE VIRAL INFECTIONS IN CHILDREN |
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Authors: | M. M. ZEITOUN A. I. HASSAN Z. M. HUSSEIN M. S. FAHMY M. RAGAB M. HUSSEIN |
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Affiliation: | Department of Paediatrics, Allexandria University, the Institute of Medical Research, and the Department of Statistics, High Institute of Public Health, Alexandria, Egypt |
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Abstract: | The hypothalamic pituitary adrenal system was studied in normal Egyptian children and in groups of children with some common viral infections including measles, chicken pox, mumps and poliomyelitis. Results showed a significant rise in plasma 17-OHCS levels in all acute viral infections. ACTH and metyrapone tests revealed that the hypothalamic-pituitary-adrenal axis was functioning adequately. The value of corticosteroids in the management of acute viral infections is discussed in the light of our clinical and laboratory findings. |
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Keywords: | Adrenalglucocorticoidfunction acute viral infections |
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