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郑州市二七区、中原区三年白血病发病因素调查
引用本文:邹典斌,宋永平,席雨人,候风喜,郭子勤,梁梅,吕潘溪,韩升高.郑州市二七区、中原区三年白血病发病因素调查[J].郑州大学学报(医学版),1990(2).
作者姓名:邹典斌  宋永平  席雨人  候风喜  郭子勤  梁梅  吕潘溪  韩升高
作者单位:河南医科大学第一附属医院内科 (邹典斌,宋永平,席雨人,候风喜,梁梅,吕潘溪),郑州市第四人民医院 (郭子勤),河南医科大学预防医学系流行病学教研室(韩升高)
摘    要:对郑州市二七区、中原区1986~1988年白血病的发病因素进行了调查。每年的调查人群数分别为449687,481206,503815人,共发现44例新发白血病。调查表明,年龄因素与发病关系明显,老年人(≥50岁)发病率明显高于中青年人。采用病例与对照1:2配对调查的方法,进行发病危险因素的单因素分析和Logistic多元回归分析,结果均显示密切接触化学品是白血病发病的重要危险因素,服用乙双吗啉是危险因素,10年内多次接触x线和遗传因素也可能和白血病发病有关。

关 键 词:白血病  发病因素  调查

The three-year investigation of the pathogenic factors of leukemia in Erqi and Zhongyuan districts of Zhengzhou
Zhou Dianbin,Shong Yongping,Xi Yuren,Hou Fengxi,Guo Zhiqin,Liang Mei,Lu Fanxi,Han Shenggao.The three-year investigation of the pathogenic factors of leukemia in Erqi and Zhongyuan districts of Zhengzhou[J].Journal of Zhengzhou University: Med Sci,1990(2).
Authors:Zhou Dianbin  Shong Yongping  Xi Yuren  Hou Fengxi  Guo Zhiqin  Liang Mei  Lu Fanxi  Han Shenggao
Institution:Zhou Dianbin,Shong Yongping,Xi Yuren,Hou Fengxi,Guo Zhiqin,Liang Mei,Lu Fanxi,Han Shenggao Department of Medicine,The First Affiliated Hospital Teaching and Research Room of Epidemiology,Department of Preventive Medicine
Abstract:Pathogenic factors of leukemia in Erqi and Zhonyuan Districts of ZhengZhoufrom 1986 to 1988 were investigated .449687,481206 and 503815 persons wereinvestigated each year respectively. Altogether 44 new cases of luekemia werefound.The results showed that age factors were related evidently to the genesisof leukemia,and the incidence of leukemia in aged persons(5 years of age)washigher than that in middle aged and young persons.The means of 1 to 2 match-ed pair investigation of cases and control was adopted.Single factor analysisand Logistic multivariate regression analysis of dangerous pathogenic factors we-re carried out.results indicated that close contact with chemicals was an impor-tant dangerous factor of the genesis of leukemia Taking in Bimolane (AT-1727)was a dangerous factor. Multople exposure to X-ray for 10 years and geneic fac-tors might also be related to the genesis of leukemia.
Keywords:leukemia  pathogenic factors  disease incidence  regression analysis
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