Induction of lesional and circulating leukocyte apoptosis by infliximab in a patient with moderate to severe psoriasis |
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Authors: | Malaviya Rama Sun Yvonne Tan Jennifer K Magliocco Melissa Gottlieb Alice B |
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Affiliation: | University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08903-0019, USA. malaviya@earthlink.net |
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Abstract: | Infliximab demonstrates high efficacy in treating psoriasis in a high proportion of patients. In this report we demonstrate induction of plaque (T cells, dendritic cells) and peripheral blood (T cells, monocytes) leukocyte apoptosis following a single infliximab infusion in a psoriasis patient. |
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