急性脑梗死患者血浆D-二聚体水平变化

目的观察急性脑梗死患者血浆D-二聚体水平的变化及临床意义。方法对71例急性脑梗死患者急性期、恢复期和64例健康体检者采用双抗体夹心法检测血浆D-二聚体水平。结果急性脑梗死患者急性期血浆D-二聚体水平：72h（1．54±0．91）mg/L、第7天（1．32±0．86）mg/L，较恢复期第15天（0．49±0．31）mg／L、第30天（0．32±0．14）mg／L和健康体检者（0．31±0．81）mg/L明显增高（t=2．576、t=2．807，P〈0．01）。结论检测血浆D-二聚体可作为急性期脑梗死病情判定及疗效观察的有效指标。

The significance of blood plasma D-Dimer level in diagnosing and treating the acute cerebral infarction patients in the community hospital

Objective To throagh observing the change of plasma D-Dimer level in the acute cerebral infarction patients to provide the experimental foundation for further research of pathology,physiology pathological process judgment and observation of curative effect.Methods To measure the plasma D-Dimer level by ELISA in 71 cases of acute wrebral infarction patients and 64 healthy controls.Results The plasma D-Dimer level in the acute cerebral infarction patients in acute period was 72h(1.54 ±0.91)mg/L、7d(1.32 ±0.86)mg/L significantly higher than 15d (0.49±0.31)mg/L30d(0.32±0.14)mg/L at resume period patients and(0.31 ±0.81)mg/L at normal controls and dropped in resume period(t =2.576,t =2.807,P＜0.01).They had significant difference.Conclusion The results indicate that acute cerebral infarction is in the manifestation of hyper coagulation,plasma D-Dimer measuring was valuable for pathological process judgment and observation of curative effect of acute cerebral infarction.