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慢性乙型重型肝炎228例中西医结合治疗临床研究
引用本文:周双男,王立福,杨慧银,李筠. 慢性乙型重型肝炎228例中西医结合治疗临床研究[J]. 临床和实验医学杂志, 2011, 10(12): 889-890,892
作者姓名:周双男  王立福  杨慧银  李筠
作者单位:1. 军医进修学院,北京,100853;解放军第三0二医院,北京,100039
2. 解放军第三0二医院,北京,100039
基金项目:国家"十一五"传染病重大专项课题"慢性重型肝炎证候规律及中西医结合治疗方案研究"
摘    要:目的通过对228例慢性乙型重型肝炎中西医结合治疗的临床研究,探讨中西医结合治疗时机以及影响疗效的因素。方法所有病例均采用中西医结合治疗措施,包括保肝、退黄、抗病毒、对症支持及中医辨证治疗,总结不同分期的疗效,对影响其预后的因素进行统计分析。结果 228例慢性乙型重型肝炎患者中,治疗总有效率44.3%;其中早期有效率80.0%,中期有效率50.4%,晚期有效率仅为10.0%。总胆红素、胆碱酯酶、白蛋白、凝血酶原活动度、总胆固醇、并发症、病情分期等指标均是影响疗效的相关因素。结论慢性乙型重型肝炎治疗有效率低,缺乏特效的治疗手段。在早中期进行中西医结合治疗可取得较好疗效。采用中西医结合治疗策略,通过中药有效控制并发症,降低病死率,是重型肝炎中西医结合治疗的主要方向。

关 键 词:慢性乙型重型肝炎  中西医结合  疗效

Clinical study on 228 patients with severe chronic hepatitis B treated by integrated traditional Chinese and western medicine
ZHOU Shuang-nan,,WANG Li-fu,YANG Hui-yin,et al.. Clinical study on 228 patients with severe chronic hepatitis B treated by integrated traditional Chinese and western medicine[J]. Journal of Clinical and Experimental Medicine, 2011, 10(12): 889-890,892
Authors:ZHOU Shuang-nan    WANG Li-fu  YANG Hui-yin  et al.
Affiliation:ZHOU Shuang-nan1,2,WANG Li-fu2,YANG Hui-yin2,et al.1 PLA Postgraduate Medical School,Beijing 100853,2 302 Hospital of PLA,Beijing 100039,China.
Abstract:Objective To explore the proper time for treatment and factors influencing the effect of 228 cases of severe chronic hepatitis B treated with integrated traditional Chinese and western medicine.Methods All these cases were treated by routine integrated traditional Chinese and western medicine including hepatocytes-protection,jaundice-reducing,antivirus,supportive care and treatment through differentiation of syndromes by TCM.The effects of different stages and the related factors to the outcome were analyse...
Keywords:Chronic severe hepatitis B  Integrated traditional and western medicine  Effection  
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