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负荷剂量的氯吡格雷治疗不稳定型心绞痛的疗效观察
引用本文:辛藏玲 宁东艳. 负荷剂量的氯吡格雷治疗不稳定型心绞痛的疗效观察[J]. 中国现代医学杂志, 2005, 15(19): 2956-2957,2960
作者姓名:辛藏玲 宁东艳
作者单位:河南省平顶山市第四人民医院(市妇幼保健院)内科,河南平顶山467000
摘    要:目的 探讨氯吡格雷(波立维)治疗不稳定型心绞痛(unstable angina,UA)的疗效.方法 128例UA患者随机分为治疗组和对照组,治疗组用常规治疗加首次波立维300mg,口服(治疗组68例).对照组用常规治疗(对照组60例),比较两组的疗效.结果 治疗组显效56例(82%),有效8例(12%),对照组显效36例(60%),有效8例(13%),两组相比差异有显著性(P<0.05).结论 UAP患者用负荷剂量的波立维治疗可取得较好的效果.

关 键 词:氯吡格雷 负荷剂量 不稳定型心绞痛
文章编号:1005-8982(2005)19-2956-02
收稿时间:2004-04-04
修稿时间:2004-04-04

Study of effect of load-dose clopidogrel on unstable angina
XIN Zang-ling, NING Dong-yan. Study of effect of load-dose clopidogrel on unstable angina[J]. China Journal of Modern Medicine, 2005, 15(19): 2956-2957,2960
Authors:XIN Zang-ling   NING Dong-yan
Affiliation:Department of Internal Medicine, the Forth Renmin Hospital of Pingdingshan, Pingdings han, He nan 467000, P.R. China
Abstract:[Objective] To study the effect of load-dose clopidogrel on unstable angina (UA). [Mehtods] 128 UA patients were random divided into therapy group (68 cases) and control group (60 cases). Patients in therapy group received general treatment in addition to clopidogrel (300mg for first dose). Patients in control group received general treatment. [Results] In therapy group, the treatment was significant effective in 56 cases (82%) and effective in other 8 cases (12%). In control group, the treatment was significant effective in 36 cases (60%) and effective in other 8 cases (13%). The differences between two groups were significant (P <0.05). [Conclusions] UA patients can receive better effect by load-dose clopidogrel than general treatment.
Keywords:clopidogrel   load-dose   unstable angina
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