Granulocyte-Macrophage Colony-Stimulating Factor for Perianal Hidradenitis Suppurativa: Report of a Case |
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| Authors: | Ahuva Sharon-Guidetti M.D. Yehiel Ziv M.D. Esther Kummer M.D. Robert Yogev M.D. Ariel Halevy M.D. |
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| Affiliation: | (1) Department of Internal Medicine “F”, Assaf Harofeh Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Zerifin, Israel;(2) Division of Surgery, Assaf Harofeh Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Zerifin, Israel;(3) Department of Surgery “B”, Assaf Harofeh Medical Center, Zerifin, 70300, Israel |
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| Abstract: | Perianal hidradenitis suppurativa is a chronic inflammatory disease associated with significantly high morbidity, which severely affects the quality of life of those patients suffering from it. We describe a 46-year-old patient with extensive, severe gluteal and perianal PHS of 28 years duration. Repeated wide excisions, fistulotomies, treatments with hyperbaric oxygen, and finally a diverting colostomy were unsuccessful. A new form of treatment with repeated perilesional injections of granulocyte-macrophage colony-stimulating factor, in conjunction with surgical procedures, was performed with excellent results. |
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| Keywords: | Perianal Hidradenitis suppurativa Granulocyte-macrophage colony-stimulating factor |
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