河南“4.26”60Co源辐射事故3例中重度骨髓型急性放射病临床报告

目的：通过对^60Co源事故3种例中重度骨髓型急性放射病（ARS）患者的剂量估算，临床经过和诊治方法的总结，以积累临床资料，方法：依据受照剂量，临床表现，实验实检测结果进行综合分析，以明确诊断，治疗上经全环境保护隔离，在有指征对症治疗的基础上，应用了造血生长因子，结果：3例病人经过83d住治疗，达到临床治愈，结论：正确的早期分类诊断和初期的积极治疗有利于安全度过极期，女病人如正逢病程极期来月预雄性激素以改变经期，可避免大出血，适时足量应用粒－巨噬细胞集落刺激因子（GM－CSF）有助造血功能恢复。

Clinical report of three cases of acute radiation sickness from a 60Co radiation source accident in Henan Province

Objective To sum up clinical experience in assessment of radiation dose,clinical course,diagnosis,and treatment of three cases of acute radiation sickness (ARS) from a ⁶⁰ Co radiation source accident on April 26 1999,in Henan Province.Method Diagnosis was carried out based on analysis of irradiation doses,clinical manifestation and laboratory test results.In therapeutic aspect,strict environment protective isolation and GM-CSP administration on the basis of comprehensive treatment were stressed.Results The 3 cases of ARS were meticulously treated for 83 days.Their clinical conditions took a favorable turn,and the therapeutic effects were good.Conclusion The correct diagnosis on severity of ARS and adopting vigorous treatment in early stage could help the patient tide over the critical stage.To avoid major hemorrhage,women patients in critical stage have to change their menstruation cycle by using male hormone.The GM-CSF should be administrated as early as possible with enough dosage for promoting early hematologic reconstruction.