| HPLC法测定注射用美洛西林钠的含量 |
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| 引用本文： | 黄汉清,秦斌. HPLC法测定注射用美洛西林钠的含量[J]. 中国药师, 2002, 5(2): 98-99 |
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| 作者姓名： | 黄汉清 秦斌 |
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| 作者单位： | 广东省深圳市药品检验所,518029 |
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| 摘 要： | 目的:建立高效液相色谱法测定注射用美洛西林钠的含量。方法:以0.025mol·L~(-1)磷酸溶液(用三乙胺调节pH值至3.0)-乙腈(80:20)为流动相,在C_(18)柱上测定美洛西林钠的含量,检测波长为220nm。结果:在50～400μg·ml~(-1)浓度范围内,线性良好(r=0.9999,n=8)。平均回收率99.4％,RSD=0.2％(n=5)。结论:本法快速、准确、重现性高。
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| 关 键 词： | 美洛西林钠 HPLC |
| 文章编号： | 1008-049X(2002)02-0098-02 |
| 修稿时间： | 2001-02-02 |
Content Determination of Mezlocillin Sodium for Injection by HPLC |
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| Huang Hanqing,Qin Bin. Content Determination of Mezlocillin Sodium for Injection by HPLC[J]. China Pharmacist, 2002, 5(2): 98-99 |
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| Authors: | Huang Hanqing Qin Bin |
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| Abstract: | Objective: To establish a HPLC method for the content determination of mezlocillin sodium for injection. Method: mezlocillin sodium was determined on C18 column with a mobile phase 0.025 mol/L phosphoric acid (pH was adjusted to 3.0 by tri-ethlamine)-acetonitrile (80:20) and detected at 220 nm. Result:The linear correlation was in a range of 50-400 ug/ml. r = 0.9999 ( n = 8). The average recovery was 99.4% , RSD = 0.22% (n=5). Conclusion: A rapid, accurate and reproducible HPLC method for the content determination of mezlocillin sodium has been established. |
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| Keywords: | Mezlocilin sodium HPLC |
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