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左旋氧氟沙星短程治疗伤寒50例
引用本文:杨建国,丁昌平,张敏,柳健,陈宝萍. 左旋氧氟沙星短程治疗伤寒50例[J]. 中国现代医学杂志, 2002, 12(3): 59-60,64
作者姓名:杨建国  丁昌平  张敏  柳健  陈宝萍
作者单位:东南大学医学院附属扬州医院,扬州,225001
摘    要:目的为了探讨伤寒短程治疗的有效药物。方法 :应用左旋氧氟沙星 (LFX) 0 .2 g口服或静脉滴注 ,2次 /d ,治疗经血培养或骨髓培养确诊的伤寒 5 0例 ,疗程 7d ;另用氧氟沙星 (OFX) 4 2例作对照 ,剂量 0 .2 g口服或静脉滴注 ,2次 /d ,疗程 7d。结果 :LFX组有效率为 10 0 % ,与OFX组 10 0 %相似 ,显效、有效病例两组间差异不显著 (P >0 .0 5 ) ,两组副作用均少而轻微。结论 :左旋氧氟沙星LFX是短程治疗伤寒的又一安全有效的药物。

关 键 词:伤寒  药物疗法

LEVOFLOXACIN FOR SHORT_COURSE TREATMENT IN 50 PATIENTS WITH TYPHOID FEVER
Yang Jianguo,Ding Changping,Zhang Min,et al.. LEVOFLOXACIN FOR SHORT_COURSE TREATMENT IN 50 PATIENTS WITH TYPHOID FEVER[J]. China Journal of Modern Medicine, 2002, 12(3): 59-60,64
Authors:Yang Jianguo  Ding Changping  Zhang Min  et al.
Affiliation:Yang Jianguo,Ding Changping,Zhang Min,et al. The Affiliated Yangzhou Hospital of Southeast University Medical College,Yangzhou 225001
Abstract:Objective:In order to study the effective drugs for short_course treatment in patients with typhoid fever.Methods:Levofloxacin (LFX) (200mg,bid) was given orally or intravenously for 7 days in the treatment of 50 patients with typhoid fever confirmed by blood and/or born marrow cultures;ofloxacin (OFX)(200mg,bid) was given orally or intravenously for 7 days in the control treatment.Results:LFX resulted in complete cure of all 50 patients with typhoid fever similar to OFX.Between LFX group and OFX group there were not significant difference( P >0.05).The adverse effects of the studied drugs were mild.Conclusions:LFX is an effective,safe drug of short_course treatment for typhoid fever.
Keywords:Levofloxacin/Treatment Effect  Ofloxacin/Treatment Effect  Typhoid Fever/Drug Therapy
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