| 结肠癌肝转移切除术后复发机制 |
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| 引用本文： | 蔡文松,徐波. 结肠癌肝转移切除术后复发机制[J]. 国际肿瘤学杂志, 2008, 35(12): 924-926 |
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| 作者姓名： | 蔡文松 徐波 |
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| 作者单位： | 广州市第一人民医院肝胆外科,510180;广州市第一人民医院肝胆外科,510180 |
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| 基金项目： | 广东省社会发展领域科技计划项目，广东省医学科学研究基金 |
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| 摘 要： | 结肠癌肝转移切除术后仍有较高的复发率.在肝部分切除之后,由于肝脏的损伤,启动了肝再生机制.肝切除术后局部血管生成增加、细胞外基质的降解、肿瘤抑制因子的减少、机体免疫力的改变、促肝细胞生长因子的作用等因素,都可能参与促进残癌生长的过程.
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| 关 键 词： | 结肠肿瘤 肝转移 肝切除术 肿瘤复发 肝再生 |
Recurrence mechanisms of colon carcinoma with hepatic metastases after hepatectomy |
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| Abstract: | The recurrence rate of colon carcinoma with hepatic metastases is high after hepatectomy.Injury of liver made by hepatectomy triggers liver regeneration and provides new circumstances including angio-genesis,degradation of extracellular matrix,reduction of tumor-inhibiting factors,variation of immune state,liver growth factors,and so on.These new factors may play roles on promoting growth of the residual carcinoma cells. |
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| Keywords: | Colon neoplasms Hepatic metastases Hepatectomy Neoplasm recurrence Liver regen-eration |
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