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No association between synapsin III gene promoter polymorphisms and multiple sclerosis in German patients
Authors:Denis A. Akkad  René Gödde  Jörg T. Epplen
Affiliation:(1) Human Genetics, Ruhr-University, 44801 Bochum, Germany
Abstract:We investigated whether the polymorphisms rs133946 and rs133945 in the promoter region of the synapsin III (SYN3) gene are associated with multiple sclerosis in German patients. Association of the SYN3 variations and haplotypes with MS is not evident in German MS patients - in contrast to a MS cohort from Italy, as reported previously. Received in revised form: 23 February 2006
Keywords:synapsin III  multiple sclerosis  SYN3  association study
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