| 复方雪莲风湿凝胶膏提取工艺研究 |
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| 引用本文： | 薛桂蓬,邢建国,赵媛,刘桂花,孙文娟.复方雪莲风湿凝胶膏提取工艺研究[J].中国现代应用药学,2012,29(2):129-133. |
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| 作者姓名： | 薛桂蓬 邢建国 赵媛 刘桂花 孙文娟 |
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| 作者单位： | 1.新疆维吾尔自治区药物研究所，乌鲁木齐 830004；2.新疆医科大学中药学院，乌鲁木齐 830002 |
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| 基金项目： | 自治区科技支疆项目(201091155) |
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| 摘 要： | 目的优选复方雪莲风湿凝胶膏提取工艺。方法采用正交试验设计,分别以蛇床子素含量、姜黄素含量和浸膏收率为指标,优化雪莲等7味药材的提取工艺;以没食子酸含量和浸膏收率为指标,优选土元和五倍子2味药的提取工艺。结果 7味药最佳提取工艺为10倍量80%乙醇,提取3次,每次1 h;2味药最佳提取工艺为10倍量水,提取3次,每次2.5 h。结论优选的提取工艺稳定、可行。
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| 关 键 词： | 蛇床子素 姜黄素 没食子酸 正交试验 提取工艺 |
| 收稿时间： | 2011/5/13 0:00:00 |
| 修稿时间： | 7/28/2011 6:17:54 PM |
Study on Extraction Process of Compound Xuelian Cataplasm |
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| XUE Guipeng,XING Jianguo,ZHAO Yuan,LIU Guihu,SUN Wenjuan.Study on Extraction Process of Compound Xuelian Cataplasm[J].The Chinese Journal of Modern Applied Pharmacy,2012,29(2):129-133. |
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| Authors: | XUE Guipeng XING Jianguo ZHAO Yuan LIU Guihu SUN Wenjuan |
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| Institution: | 1.Xinjiang Institute of Meteria Medica, Urumqi 830004, China; 2.Xinjiang Medical University, Urumqi 830002, China |
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| Abstract: | OBJECTIVE To optimize the extraction process of Compound Xuelian Cataplasm. METHODS Orthogonal experimental design was used for the optimization, the extract yield, the content of osthole and curcumin were taken as the indexes in extracting process of seven herb medicines; the extract yield and the content of gallic acid were taken as the indexes in extracting process of two herb medicines. RESULTS The optimum extraction progress was as follows: seven herb medicines were extracted 3 times for 1 hour with 10 times amount of 80% alcohol; two herb medicines were extracted 3 times for 2.5 hour with 10 times amount of water. CONCLUSION The optimum extraction process was stable and feasible. |
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| Keywords: | osthole curcumin gallic acid orthogonal test extraction technique |
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