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Trends in radiation protection in CT: Present and future status
Authors:Bernhard Bischoff  Franziska Hein  Tanja Meyer  Martin Hadamitzky  Stefan Martinoff  Albert Schömig  Jörg Hausleiter
Institution:1. Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Lazarettstrasse 36, 80636 Munich, Germany;2. Institut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Lazarettstrasse 36, 80636 Munich, Germany;1. Department of Medical and Occupational Radiation Protection, Federal Office for Radiation Protection, Ingolstädter Landstraße 1, D-85764 Oberschleissheim, Germany;2. Department of Clinical Radiology, Grosshadern Clinic, Hospital of the Ludwig-Maximilians University, Marchioninistraße 15, D-81377 Munich, Germany;1. Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France;2. Pediatric Radiology Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France;3. Epicime-Clinical Investigation Center 1407 de Lyon, Inserm, Service de Pharmacologie Clinique, CHU Lyon, Bron, France;4. Laboratory of Biometrics and Evolutionary Biology, National Center for Scientific Research, UMR 5558, Villeurbanne, France;1. School of Health and Rehabilitation Sciences, College of Medicine, The Ohio State University, Columbus, Ohio;2. College of Medicine, The Ohio State University, Columbus, Ohio;1. Department of radiology, Taipei Veterans general hospital, 201, Shipai Road, Section 2, 11217 Taipei, Taiwan;2. School of medicine, National Yang Ming university, Taipei, Taiwan;3. Siemens AG, healthcare sector, angiography and interventional X-Ray systems, Forchheim, Germany
Abstract:With the introduction of modern multislice scanner generations, computed tomography (CT) has emerged as a useful tool for evaluation of the coronary arteries. A common application of coronary CT angiography (CCTA) is the examination of patients with intermediate pretest probability for obstructive coronary artery disease. Despite the widespread use of cardiac CT examinations in clinical practice, concern remains about the exposure to ionizing radiation and its potential hazards. Therefore, radiation dose and strategies for dose reduction have become an important focus of interest. Several smaller analyses have shown an effective radiation dose between 6.4 and 27.8 mSv for spiral CCTA image acquisition. The international Prospective Multicenter Study On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy I (PROTECTION I) study, the largest observational study on radiation dose estimates of cardiac CT so far, determined radiation dose estimates of CCTA, as well as the effect of different strategies to reduce dose in clinical practice. The median dose-length-product of 1965 CCTA examinations was 885 mGy × cm, which corresponds to a median estimated effective radiation dose of 12 mSv. However, a large variation in dose between study sites was observed, indicating a large potential to reduce dose for individual sites. Several dose-saving scanning techniques and algorithms have been developed. This article discusses these strategies as well as their effect on radiation dose and image quality. Because the contrast-enhanced CT angiography is the largest part of the total study dose, the following described strategies focus on radiation dose reduction for CCTA image acquisition.
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