成人颅内非典型畸胎瘤样/横纹肌样瘤的MRI表现与病理对照(附2例报告及文献复习)

目的探讨成人颅内非典型畸胎瘤样/横纹肌样瘤的影像和病理特征。资料与方法回顾性分析2例经手术病理证实的成人颅内非典型畸胎瘤样/横纹肌样瘤患者MRI资料并文献复习。结果 1例MRI表现类似脑膜瘤征象:实质部分呈等T1、等T2信号,扩散加权成像(DWI)高信号,宽基底与脑膜接触和均匀强化;又有原始神经外胚叶肿瘤(PNET)特点:实性部分呈等T1、等T2伴多房小囊变,DWI高信号;室管膜强化提示脑脊液播散。另1例囊实性病变类似胶质瘤,但实质部分T2接近等信号,有微囊和明显均匀强化,又类似神经节细胞胶质瘤。两例病理均见肌母细胞和细胞丰富能解释等T1、等T2信号和DWI高信号;血管增生明显从而强化显著;灶性坏死易见类似胶质瘤,因此,MRI表现基本能反映病理学变化。结论成人颅内幕上非典型畸胎瘤样/横纹肌样瘤的MRI表现类似于髓母细胞瘤、PNET、恶性胶质瘤及神经节细胞胶质瘤,但成分更混杂、更具中枢神经系统播散潜力为本病特点,发生在幕上、多发可能有助于本病定性诊断,确诊依赖病理组织学检查。

MRI and Pathological Features of Intracranial Atypical Teratoid/Rhabdoid Tumors in Adult Patients(Report of 2 cases and Literature Review)

Objective To investigate the MR and pathological features of intracranial atypical teratoid/rhabdoid tumors(AT/RT) in adults.Materials and Methods Two cases of AT/RT proved by pathology were analyzed,and literatures were reviewed.Results For case 1,some MRI features were similar to meningioma:the solid portion of lesion was isointensity on T1 and T2,heperintensity on DWI,wide basal adhesion to meninge and homogeneous enhancement;some MR features were similar to PNET:the solid portion of lesion showed isoint...