| 卡马西平血清样品的稳定性考察 |
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| 引用本文： | 曾雪花,邓小煌,郁相云,钟建华.卡马西平血清样品的稳定性考察[J].临床医学工程,2009,16(12):62-63. |
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| 作者姓名： | 曾雪花 邓小煌 郁相云 钟建华 |
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| 作者单位： | 深圳市龙岗中心医院,广东深圳518116 |
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| 摘 要： | 目的考察卡马西平血清样品不同保存条件对血清药物浓度的影响。方法取癫痫患者血清样品,在取血当时、室温(28±3)℃保存1d、2d、3d或冷藏(4±1)℃保存1d、3d、7d后,用荧光偏振免疫法(FPIA)测定血清卡马西平浓度并进行比较,考察其稳定性。结果室温保存1d、2d、3d或冰箱冷藏保存1d、3d、7d的血清测定结果均与取血当时测定结果无统计学差异。结论卡马西平血清样品在室温下可稳定保存三天、冷藏条件下可稳定保存七天。
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| 关 键 词： | 卡马西平 荧光偏振免疫法 血药浓度 稳定性 |
Study on Stability of Carbamazepine Concentrations in Serum Samples |
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| Abstract: | Objective To investigate the effects on serum drug concentrations of carbamzepine with different storage requirements of serum sample.Methods The serum samples from epileptic patients were stored at normal temperature (28 ±3)℃ for 1 day,2 days and 3 days or in refrigeration (4 ±1)℃ for 1 day,3 days and 7 days,then these samples were determied by FPIA and the results were compared with the new ones.Results Compared with the new samples,the samples which were stored at normal temperature for 3 days or for 7 days in refrigeration were no significant differences.Conclusion Serum samples of carbamzepine can be stored stably at normal temperature for 3 day or in refrigeration for 7 days. |
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| Keywords: | carbamzepine FPIA serum drug concentrations stability |
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