二氧化碳激光联合重组人干扰素α-2b治疗60例尖锐湿疣患者的临床观察

目的：观察尖锐湿疣（CA）应用二氧化碳激光联合重组人干扰素α-2b治疗的有效性、安全性、复发率。方法：将筛选的120例尖锐湿疣患者随机分为试验组和对照组。试验组和对照组患者均行二氧化碳激光术局部治疗。试验组60例患者加用重组人干扰素α-2b皮损局部注射。观察两组的治愈率、复发率。结果：试验组术后治愈率为91．67％，随访复发率为8．33％。对照组治愈率为68．34％，随访复发率为31．67％。两组间治愈率、复发率比较，均有显著性统计学差异（P〈0．01）。结论：应用二氧化碳激光联合重组人干扰素α-2b局部注射对尖锐湿疣疗效较好，并且术后复发率较低。

Carbon dioxide laser combined with recombinant human interferon a- 2b in the treatment of condyloma acuminate

Objectives： To observe the efficacy, safety, recurrence rate of carbon dioxide laser combined with recombinant human interferon a-2b injection in the treatment of condyloma acuminate （CA）. Method： 120 CA patients were randomly di vided into the experimental group and the control group, 60 in each group. Both groups underwent topical treatment of carbon di oxide laser surgery. In addition, the experimental group were treated with recombinant human interferon a - 2b injection. The cure and recurrence rates were observed. Results： Compared with the control group, the experimental group showed higher cure rate （91.67% compared with 68.34% ） and lower postoperative follow up recurrence rate （8.33% compared with 31.67% ）. Those differences were statistically significant （ P 〈 0.01 ）. Conclusion： Carbon dioxide laser combined with recombinant human interferon a- 2b injection is a good treatment for condyloma acuminate. It is a treatment featuring low recurrence rate