公共场所人群嗜肺军团菌血清抗体水平的调查研究

目的:了解温州市部分人群血清嗜肺军团菌的抗体阳性率以及嗜肺军团菌抗体(LP1～10)的分布特点。方法:采用微量凝集试验(MAT)测定就业人员血清中嗜肺军团菌1至10型抗体滴度。结果:1000例人群血清抗嗜肺军团菌抗体阳性89例,总阳性率为8.9%,其中暴露人群血清中嗜肺军团菌感染的阳性率11.6%(58/500),对照人群血清中嗜肺军团菌感染的阳性率6.2%(31/500),阳性率有显著性差异,暴露人群高于对照人群(χ2=8.991,P<0.05)。在阳性结果中,2种及以上血清型同时阳性为17份,占19.10%(17/89)。结论:我市健康人群普遍存在不同程度和不同血清型的嗜肺军团菌隐性感染,使用中央空调的场所是嗜肺军团菌感染的高危场所,应加强监测。

Investigation on legionella pneumophila serogroup antibody level of population in public places

Objective:To investigate Legionella antibody positive rate in part of the crowd and Legionella pneumophila antibodies(LP1～10) distribution characteristics in Wenzhou city.Methods: The Legionella pneumophila antibodies(LP1～10) titers of employment population were detected by MAT.Results: In 1000 cases of human serum anti-legionella pneumophila antibodies,89 cases were positive,the positive rate was 8.9%,while the positive rate of legionella pneumophila was 11.6%(58/500) in exposed population and 6.2%(31/500) in control group,there were significant differences between exposed populations and the control group(χ2=8.991,P<0.05).In positive results,2 or more serotypes were found all positive in 17 cases,accounting for 19.10%(17/89).Conclusion: Legionella pneumophila infection was generally found in healthy population in the city with different degrees and serotypes.The place using central air-conditioner was Legionella pneumophila infection high-risk place,which should be strengthened monitoring.