Hypoglycemia symptoms are reduced in hospitalized patients with diabetes |
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| Affiliation: | 1. First Department of Propaedeutic Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece;2. Department of Internal Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany;3. Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece;1. Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China;2. Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China;3. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China;4. NHMRC Clinical Trial Centre, Faculty of Medicine and Health, University of Sydney, Australia;5. Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China |
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| Abstract: | AimsHospitalized patients with diabetes are have an impaired ability to detect hypoglycemia events. The purpose of this study was to compare hypoglycemia symptom scores (HSS) in hospitalized patients with diabetes after a documented blood glucose (BG) <70 mg/dl with recalled HSS with outpatient hypoglycemia events.MethodsNon-critically ill hospitalized patients with diabetes grouped as symptomatic (n = 23) or asymptomatic (n = 32) at time of index hypoglycemia completed a standardized HSS-Questionnaires (HSS-Q) related to the inpatient event and to recall of symptoms with outpatient hypoglycemia.ResultsAfter controlling for BG at time of index hypoglycemia (49.8 ± 11.4 vs. 57.4 ± 6.8 mg/dl, p = 0.02), symptomatic patients reported higher HSS than asymptomatic patients with the inpatient event (11.6 ± 7.3 vs. 1.5 ± 3.4, p < 0.001) and in the outpatient setting (13.9 ± 8.6 vs. 10.1 ± 10.6, p < 0.01). Recurrent hypoglycemia was more frequent in asymptomatic patients (13% vs. 44%, p = 0.015) during the hospitalization.ConclusionsCompared to symptomatic patients, asymptomatic patients had lower inpatient and outpatient HSS and more frequent recurrent hypoglycemia events. These results suggest modification of glycemic management strategies in high risk patients to reduce risk for hypoglycemia events. |
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