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原发性偏侧面肌痉挛与Meige综合征及A型肉毒素对其治疗的研究现状
引用本文:张晗,刘航,刘婉晴,杨婧艺,尹静茹,马英.原发性偏侧面肌痉挛与Meige综合征及A型肉毒素对其治疗的研究现状[J].实用药物与临床,2020,23(3):276-281.
作者姓名:张晗  刘航  刘婉晴  杨婧艺  尹静茹  马英
作者单位:中国医科大学附属盛京医院神经内科,辽宁沈阳 110004
基金项目:辽宁省自然科学基金;国家自然科学基金;沈阳市科技计划
摘    要:对国内外关于原发性偏侧面肌痉挛及Meige综合征和A型肉毒素对其治疗的文献进行回顾性分析,阐述原发性偏侧面肌痉挛及Meige综合征的发病机制、诊断及治疗现状,重点阐述A型肉毒毒素注射治疗原发性偏侧面肌痉挛及Meige综合征的适应证、药物使用浓度、药效、药效持续时间、注射位点、并发症及对情绪的影响等。明确A型肉毒毒素治疗原发性偏侧面肌痉挛及Meige综合征的优越性。

关 键 词:A型肉毒毒素  原发性偏侧面肌痉挛  MEIGE综合征

Current status of primary hemifacial spasm and Meige syndrome and their treatment with botulinum toxin type A
ZHANG Han,LIU Hang,LIU Wan-qing,YANG Jing-yi,YIN Jing-ru,MA Ying.Current status of primary hemifacial spasm and Meige syndrome and their treatment with botulinum toxin type A[J].Practical Pharmacy and Clinical Remedies,2020,23(3):276-281.
Authors:ZHANG Han  LIU Hang  LIU Wan-qing  YANG Jing-yi  YIN Jing-ru  MA Ying
Institution:(Department of Neurology,Shengjing Hospital of China Medical University,Shenyang 110004,China)
Abstract:In this review,a retrospective analysis of some literatures is performed concerning primary hemifacial spasm,Meige syndrome and their treatment with botulinum toxin type A.The pathogenesis,diagnosis and treatment status of primary hemifacial spasm and Meige syndrome are described.Besides,the review emphasizes the indications of botulinum toxin type A,effective concentration,efficacy,duration of efficacy,injection site,complications and effects on emotions,aiming to determine the superiority of botulinum toxin type A in the treatment of primary hemifacial spasm and Meige syndrome.
Keywords:Botulinum toxin type A  Primary hemifacial spasm  Meige syndrome
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