An unusual intranuclear structure (? viral nucleocapsid) in the brain in subacute sclerosing panencephalitis |
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| Authors: | A. D. Dayan Swati Majumdar W. Hughes K. W. G. Heathfield |
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| Affiliation: | Department of Neuropathology, The National Hospitals, London;Oldchurch Hospital, Romford |
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| Abstract: | A brain biopsy was examined from a 7 year old boy with subacute sclerosing panencephalitis. Intranuclear deposits of measles antigens were demonstrated in parenchymal cells by immunofluorescence. Electron microscopy showed viral nucleocapsids in nucleoliform inclusions and unusual rod-like intranuclear structures which resemble structures previously described only in tissue cultures infected with measles virus. |
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