中西医治疗痤疮的临床疗效及对患者负性情绪和生活质量的影响

目的: 探讨中西医结合治疗痤疮的临床疗效及对患者负性情绪及生活质量的影响。 方法: 将128例痤疮患者随机分入对照组与观察组,给予对照组患者常规西医治疗措施,观察组患者接受中西医结合治疗。采用抑郁自评量表（SDS）和焦虑自评量表（SAS）评估负性情绪,采用皮肤病生活质量指数（DLQI）评估患者生活质量,比较两组临床疗效、治疗前后负性情绪及生活质量的改变。 结果: 观察组治疗总有效率显著高于对照组（75.8% vs 56.5%,P<0.05）;治疗后观察组SDS及SAS评分分别为（34.09±2.21）及（38.13±5.19）,显著低于对照组（38.17±2.64）和（46.80±5.76）,差别具有统计学意义（P<0.05）;治疗后观察组DLQI症状与感受、日常活动、休闲娱乐、工作和学习、人际关系、治疗及总分分别为（0.98±0.34）,（0.63±0.37）,（1.01±0.36）,（0.62±0.39）,（0.85±0.31）,（0.78±0.31）,（7.21±1.38）,对照组分别为（1.43±0.62）,（1.17±0.45）,（1.35±0.46）,（0.98±0.44）,（1.12±0.36）,（1.17±0.53）,（9.43±1.65）,差别具有统计学意义（P<0.05）。 结论: 在西医治疗基础上给予中药治疗,可显著提高临床疗效并改善患者负性情绪及生活质量。

Effect of Traditional Chinese Combined with Western Medicine in Treatment of Acne and Influence for Negative Emotion and Life Quality

Objective: To explore the effect of traditional chinese combined with western medicine in treatment of acne and the influence for negative emotion and life quality. Method: One hundred and twenty eight cases with acne were randomly divided into control group and experience group. Control group received routine western medicine therapy and experience group were given traditional chinese combined with western medicine treatment. Pepression self rating scale(SDS), self assessment scales(SAS) scores and dermatology life quality index(DLQI) scale were used to evaluate negative emotion and life quality. Clinical effect and the change of negative emotion were compared between two groups. Result: The effective rates in experience group was much higher than that in control group (75.8% vs 56.5%,P<0.05);after treatment,SDS and SAS scores in experience group were (34.09±2.21)and (38.13±5.19),of which were much lower than those in control group (38.17±2.64 and 46.80±5.76,P<0.05). The symptoms and feeling,daily activity,leisure entertainment,work and study,interpersonal relationship,therapy and total score of DLQI were(0.98±0.34),(0.63±0.37),(1.01±0.36),(0.62±0.39),(0.85±0.31),(0.78±0.31),(7.21±1.38) in experience group,and (0.98±0.34),(0.63±0.37),(1.01±0.36),(0.62±0.39),(0.85±0.31),(0.78±0.31),(7.21±1.38)in control group (P<0.05). Conclusion: Traditional chinese combined with western medicine for acne greatly improve the clinical effect,negative emotion and life quality.