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血管束植入移植神经修复周围神经缺损的实验研究
引用本文:赵德伟 杜国君. 血管束植入移植神经修复周围神经缺损的实验研究[J]. 中华骨科杂志, 1996, 16(3): 172-174
作者姓名:赵德伟 杜国君
作者单位:大连铁路医院骨科,齐齐哈尔铁路医院
摘    要:51只健康中国本兔随机分为实验组和对照组.在相同的实验条件下,用植入血管和不植入血管的游离神经移植修复3cm长坐骨神经缺损.术后3,7,14天发现移植神经较快的再血管化.分别在术后第4,8,20周做神经电生理,组织形态学观察.神经电生理指标和再生轴索,经统计学分析显示实验组明显优于对照组(P值<0.01).结果表明:再血管化程度和良好血供能有效地促进周围神经的再生.

关 键 词:周围神经缺损  自体神经  血管束植入  移植

ImplantationofVascularBundleintotheFreeNerveGraftsfortheRepairofPeripheralNerveDefects
ZhaoDewei,DuGuojun,ZhangXiaoming,et al.. ImplantationofVascularBundleintotheFreeNerveGraftsfortheRepairofPeripheralNerveDefects[J]. Chinese Journal of Orthopaedics, 1996, 16(3): 172-174
Authors:ZhaoDewei  DuGuojun  ZhangXiaoming  et al.
Affiliation:ZhaoDewei,DuGuojun,ZhangXiaoming,etal.DepartmentofOrthopaedics,DalianRailwayHospi-tal,Dalian116001
Abstract:Fiftyonehealthyrabbitswererandomlydividedintotheexperimentalandthecontrolgroups.Underidenticalexperimentalconditions,freenervegraftswithandwithoutvascularbundleim-plantationwereusedtorepair3cmSciaticNervedefects.Rapidrevascularizationinthenervegraftswasobservedatthe3th,7thand14thdaysafteroperation.Theelectrophysiologicalandmorphometricstud-ieswerecariedoutatthe4th,8thand20thweeksaftertheoperation.Theelectrophysiologicalindexandregeneratingaxonsshowedstatisficalysignificantbeterresultsthanthatofthecontrolgroup(P<0.01).Thisstudysuggestedthat,thedegreeofvascularizationandsuficientbloodsupplydideffective-lypromotetheregenerationofperipheralnerve.
Keywords:PeripheralnervedefectFreenerveVascularbundleimplantationTransplantation
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