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硫酸镁注射液细菌内毒素检查法的可行性研究
引用本文:李凤华,张克俊.硫酸镁注射液细菌内毒素检查法的可行性研究[J].安徽医药,2003,7(1):40-41.
作者姓名:李凤华  张克俊
作者单位:安徽省和县人民医院药剂科,和县,238200
摘    要:目的:建立硫酸镁注射液的细菌内毒素检测方法。方法:按《中国药典》二部2000年版附录细菌内毒素检查法,考察硫酸镁注射液对细菌内毒素法检查的干扰作用。结果:硫酸镁注射液稀释10倍,对细菌内毒素法无干扰作用。结论:细菌内毒素检查法可代替家兔热原检查法。

关 键 词:硫酸镁注射液  细菌内毒素  检查法  可行性研究  抗惊厥药

The researches on the feasibility for the bacterial endotoxin inspection method of magnesium sulfate injection
LI Feng Hua,ZHANG Ke Jun.The researches on the feasibility for the bacterial endotoxin inspection method of magnesium sulfate injection[J].Anhui Medical and Pharmaceutical Journal,2003,7(1):40-41.
Authors:LI Feng Hua  ZHANG Ke Jun
Abstract:AIM To establish a bacterial endotoxin test of magnesium sulfate injection. METHODS To inspect bacterial endotoxin according to the method in addend of China Pharmacopoeia (second part) 2000 edition, the interference of magnesium sulfate injection to the process of bacteria endotoxin test was studied. RESULTS Magnesium sulfate injection has no interference to the bacterial endotoxins test, when it is diluted for 10 times. CONCLUSIONS Bacteria endotoxin test could be used in place of the rabbit for pyrogen test of magnesium sulfate injection.
Keywords:magnesium sulfate injection  bacterial endotoxin test  pyrogen test  interfere test
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