| 地黄寡糖抗糖尿病药理作用及机制研究回顾 |
| |
| 引用本文： | 张汝学,周金黄,贾正平,张永祥.地黄寡糖抗糖尿病药理作用及机制研究回顾[J].中药药理与临床,2003,19(2):48-48,F003,14. |
| |
| 作者姓名： | 张汝学 周金黄 贾正平 张永祥 |
| |
| 作者单位： | 1. 兰州军区兰州总医院全军临床药理基地,兰州,730050
2. 军事医学科学院毒物药物研究所,北京,100850 |
| |
| 摘 要： | 现代医学对糖代谢的过程及其调节机制已较明确，并正在走向深入。糖代谢是机体自稳机能(homoostasis)的一个重要方面，Besedovsky等(1977)以神经内分泌系统与免疫系统之间的相互作用及其物质基础为依据，提出了“神经内分泌免疫调节”(neuroenctocrine-immuno-modulation，NIM)网络学说，这个学说的实质是机体神经系统、内分泌系统与免疫系统之间具有共
|
| 关 键 词： | 地黄寡糖 药理作用 糖代谢 抗糖尿病机制 |
Review of the study of anti-diabetic effects and related mechanism of Rehmannia glutinosa oligosaccharides |
| |
| Zhang Ruxue,Zhou Jinhuang ,Jia Zhengping,Zhang Yongxiang.Review of the study of anti-diabetic effects and related mechanism of Rehmannia glutinosa oligosaccharides[J].Pharmacology and Clinics of Chinese Materia Medica,2003,19(2):48-48,F003,14. |
| |
| Authors: | Zhang Ruxue Zhou Jinhuang Jia Zhengping Zhang Yongxiang |
| |
| Institution: | Zhang Ruxue,Zhou Jinhuang 1,Jia Zhengping,Zhang Yongxiang 1 |
| |
| Abstract: | Objevtive: The study of anti-diabetic effect and related mechanism of Rehmannia glutinosa oligosaccharides(ROS) under the guide of the theory of neuroendocrine-immuno modulation(NIM) was reviewed in this paper. Results: ROS showed the preventive effect of the glucose- or adrenaline- induced hyperglycemia and the hypoglycemic effect in alloxan-induced diabetic rats. ROS also improved the impaired glucose metabolism in thymectomized and aged rats. Conclusion: ROS is a new component with hypoglycemic effect from Rehmannia glutinosa. |
| |
| Keywords: | Rehmannia glutinosa oligosaccharides(ROS) anti-diabetic neuroendocrine-immuno modulation(NIM) glucose homeostasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
